Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9304692 | 1.00 | KMT2A (0.53) | KMT2ATDP1MEN1L3MBTL1CYP3A4 | |
| SCHEMBL4284968 | 0.91 | KMT2A (0.62) | KMT2ATDP1MEN1L3MBTL1CYP3A4 | |
| SCHEMBL11013802 | 0.91 | KMT2A (0.58) | KMT2ATDP1MEN1L3MBTL1CYP3A4 | |
| SCHEMBL9297822 | 0.89 | CYP3A4 (0.52) | KMT2ATDP1MEN1L3MBTL1CYP3A4 | |
| SCHEMBL8912455 | 0.86 | PARP10 (0.50) | KMT2ATDP1MEN1L3MBTL1CYP3A4 | |
| SCHEMBL9305285 | 0.86 | PARP10 (0.50) | KMT2ATDP1MEN1L3MBTL1CYP3A4 | |
| SCHEMBL9303618 | 0.84 | GPR52 (0.46) | KMT2ATDP1MEN1L3MBTL1CYP3A4 | |
| SCHEMBL11786917 | 0.84 | F2 (0.47) | KMT2ATDP1MEN1L3MBTL1CYP3A4 | |
| SCHEMBL9734037 | 0.84 | MEN1 (0.49) | KMT2ATDP1MEN1L3MBTL1CYP3A4 | |
| SCHEMBL9736600 | 0.84 | MEN1 (0.49) | KMT2ATDP1MEN1L3MBTL1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304667-A | Cyclosiloxanes containing mesogenic side groups | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1994-04-19 | — | — | US | disclosed |
| US-5221759-A | CYCLOSILOXANES CONTAINING MESOGENIC SIDE GROUPS | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1993-06-22 | — | — | US | disclosed |