Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301792 | 0.93 | SMN1; SMN2 (0.43) | SMN1; SMN2HPGDHTTALDH1A1CYP2C19 | |
| SCHEMBL9301436 | 0.92 | SMN1; SMN2 (0.45) | SMN1; SMN2HPGDHTTALDH1A1CYP2C19 | |
| SCHEMBL7769114 | 0.89 | CYP2C19 (0.46) | SMN1; SMN2HPGDHTTALDH1A1CYP2C19 | |
| SCHEMBL7769118 | 0.84 | NPC1 (0.50) | SMN1; SMN2HPGDHTTALDH1A1NPC1 | |
| SCHEMBL7813558 | 0.84 | CYP2C19 (0.44) | SMN1; SMN2ALDH1A1CYP2C19LMNAKMT2A | |
| SCHEMBL7813714 | 0.83 | CYP2C19 (0.39) | SMN1; SMN2HPGDHTTALDH1A1CYP2C19 | |
| SCHEMBL7776791 | 0.81 | CYP2C19 (0.52) | SMN1; SMN2HTTALDH1A1CYP2C19LMNA | |
| SCHEMBL7769133 | 0.79 | LMNA (0.51) | SMN1; SMN2ALDH1A1CYP2C19LMNAKMT2A | |
| SCHEMBL7773269 | 0.79 | CYP2C19 (0.50) | SMN1; SMN2ALDH1A1CYP2C19LMNAKMT2A | |
| SCHEMBL7769149 | 0.79 | CYP2C19 (0.47) | CYP2C19LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5284948-A | Drug hapten analogues for immunoassays | EASTMAN KODAK COMPANY (US) | 1994-02-08 | — | — | US | claimed |
| EP-0517325-A2 | Drug hapten analogues for immunoassays | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1992-12-09 | — | — | EP | claimed |