Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 15/20 | 0.63 |
| ▸ | PLG | P00747 | 11/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 10/20 | 0.54 |
| ▸ | PLAT | P00750 | 10/20 | 0.54 |
| ▸ | F2 | P00734 | 9/20 | 0.54 |
| ▸ | KLK1 | P06870 | 7/20 | 0.54 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302818 | 0.91 | FGF1 (0.54) | PLAUPLGPRSS1PLATF2 | |
| SCHEMBL9303249 | 0.90 | PLAU (0.60) | PLAUPLGPRSS1PLATF2 | |
| SCHEMBL9303274 | 0.84 | PLAU (0.62) | PLAUPLGPRSS1PLATF2 | |
| SCHEMBL7335597 | 0.82 | PLAU (0.74) | PLAUPLGPRSS1PLATF2 | |
| SCHEMBL9305495 | 0.81 | PLAU (0.54) | PLAUPLGPRSS1PLATF2 | |
| SCHEMBL9302624 | 0.81 | PLAU (0.53) | PLAUPLGPRSS1PLATF2 | |
| SCHEMBL7335327 | 0.81 | PLAU (0.72) | PLAUPLGPRSS1PLATF2 | |
| SCHEMBL9303405 | 0.81 | NPC1 (0.48) | PLAUPLGPLATF2KLK1 | |
| SCHEMBL9303344 | 0.80 | PLAU (0.74) | PLAUPLGPRSS1PLATF2 | |
| SCHEMBL28742391 | 0.80 | PLAU (0.75) | PLAUPLGPRSS1PLATF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352704-A | Antiviral agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0434432-B1 | Guanidinobenzene derivatives | BANYU PHARMA CO LTD (JP) | 1994-05-04 | — | — | EP | disclosed |
| EP-0434432-A1 | Guanidinobenzene derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-06-26 | — | — | EP | disclosed |