Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL503906 | 0.80 | KMT2A (0.48) | ALDH1A1GAAKMT2ATDP1ALOX15 | |
| SCHEMBL5511986 | 0.79 | ALDH1A1 (0.52) | ALDH1A1GAAKMT2ATDP1HPGD | |
| SCHEMBL5508368 | 0.79 | POLB (0.50) | ALDH1A1GAAKMT2ATDP1ALOX15 | |
| SCHEMBL27708258 | 0.78 | ALDH1A1 (0.55) | ALDH1A1KMT2AKDM4ECA12CA9 | |
| SCHEMBL11294874 | 0.78 | ALDH1A1 (0.55) | ALDH1A1KMT2AKDM4ECA12CA9 | |
| SCHEMBL11288233 | 0.78 | ALDH1A1 (0.55) | ALDH1A1KMT2AKDM4ECA12CA9 | |
| SCHEMBL11291690 | 0.78 | ALDH1A1 (0.55) | ALDH1A1KMT2AKDM4ECA12CA9 | |
| SCHEMBL20522793 | 0.76 | FOLH1 (0.51) | ALDH1A1GAAKMT2ATDP1ALOX15 | |
| SCHEMBL8582632 | 0.76 | CYP2C19 (0.53) | ALDH1A1SMN1; SMN2POLBSRC | |
| SCHEMBL4086184 | 0.76 | CYP2C19 (0.53) | ALDH1A1SMN1; SMN2POLBSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5324648-A | Anticoagulants; antitumor agents | GEORGIA TECH RESEARCH CORPORATION (US) | 1994-06-28 | — | — | US | disclosed |