Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 14/20 | 0.58 |
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 4/20 | 0.47 |
| ▸ | PPARA | Q07869 | 3/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9304263 | 1.00 | ALOX5 (0.58) | ALOX5PTGESPPARGPPARANR1I2 | |
| SCHEMBL16583032 | 1.00 | ALOX5 (0.58) | ALOX5PTGESPPARGPPARANR1I2 | |
| SCHEMBL9303661 | 0.91 | ALOX5 (0.53) | ALOX5PTGESPPARGPPARANR1I2 | |
| SCHEMBL9303672 | 0.91 | ALOX5 (0.53) | ALOX5PTGESPPARGPPARANR1I2 | |
| SCHEMBL9303231 | 0.91 | ALOX5 (0.52) | ALOX5PTGESPPARGPPARANR1I2 | |
| SCHEMBL16583051 | 0.88 | ALOX5 (0.65) | ALOX5PTGESPPARGPPARANR1I2 | |
| SCHEMBL20819466 | 0.86 | ALOX5 (0.54) | ALOX5PTGESPPARGPPARANR1I2 | |
| SCHEMBL16583013 | 0.85 | AKT1 (0.48) | ALOX5PTGESPPARGPPARANR1I2 | |
| SCHEMBL16583014 | 0.85 | AKT1 (0.48) | ALOX5PTGESPPARGPPARANR1I2 | |
| SCHEMBL16583033 | 0.85 | PPARA (0.58) | ALOX5PTGESPPARGPPARANR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347028-A | Highly functionalized polycyclosiloxanes and their polymerization into thermally reversible living rubbers | TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5318993-A | Antihyperlipidemic benzoquinones | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-06-07 | — | — | US | disclosed |
| US-5298589-A | Polycyclosiloxanes and polydimethylsiloxane with catalysts | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 1994-03-29 | — | — | US | disclosed |
| WO-1994002536-A1 | POLYCYCLOSILOXANES AND THERMALLY REVERSIBLE LIVING SILICONE RUBBERS | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 1994-02-03 | — | — | WO | disclosed |