Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10727047 | 0.79 | GAA (0.59) | HDAC3ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL20914987 | 0.79 | ALDH1A1 (0.59) | HDAC3ALDH1A1PKMSMN1; SMN2MEN1 | |
| SCHEMBL20914970 | 0.79 | ALDH1A1 (0.59) | HDAC3ALDH1A1PKMSMN1; SMN2MEN1 | |
| SCHEMBL1531620 | 0.79 | GAA (0.57) | HDAC3ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL14996212 | 0.78 | SMN1; SMN2 (0.81) | HDAC3ALDH1A1PKMSMN1; SMN2MEN1 | |
| SCHEMBL23099259 | 0.78 | ERCC5 (0.44) | ALDH1A1PKMSMN1; SMN2KMT2AERCC5 | |
| SCHEMBL31687700 | 0.78 | ERCC5 (0.44) | ALDH1A1PKMSMN1; SMN2KMT2AERCC5 | |
| SCHEMBL4382929 | 0.78 | GAA (0.59) | HDAC3ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL18825664 | 0.78 | GAA (0.59) | HDAC3ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL18825687 | 0.78 | GAA (0.59) | HDAC3ALDH1A1MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5344974-A | Process for the preparation of N-acyl derivatives of 5-aminolevulinic acid, as well as the hydrochloride of the free acid | SUDZUCKER AKTIENGESELLSCHAFT MANNHEIM/OCHENSFURT (DE) | 1994-09-06 | — | — | US | disclosed |