Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303508 | 1.00 | ALDH1A1 (0.49) | ALDH1A1ITGB1ITGA4TDP1L3MBTL1 | |
| SCHEMBL9303427 | 0.96 | ALDH1A1 (0.48) | ALDH1A1ITGB1ITGA4TDP1L3MBTL1 | |
| SCHEMBL9304003 | 0.96 | ALDH1A1 (0.48) | ALDH1A1ITGB1ITGA4TDP1L3MBTL1 | |
| SCHEMBL9303361 | 0.80 | POLB (0.51) | ALDH1A1ITGB1ITGA4TDP1GAA | |
| SCHEMBL9303354 | 0.80 | POLB (0.51) | ALDH1A1ITGB1ITGA4TDP1GAA | |
| SCHEMBL13525015 | 0.76 | ALDH1A1 (0.60) | ALDH1A1L3MBTL1GAACYP2C9TSHR | |
| SCHEMBL9304457 | 0.75 | HPGD (0.54) | ALDH1A1TDP1GAAHPGDKDM4E | |
| SCHEMBL9304449 | 0.75 | HPGD (0.54) | ALDH1A1TDP1GAAHPGDKDM4E | |
| SCHEMBL9305453 | 0.74 | ITGB1 (0.66) | ALDH1A1ITGB1ITGA4TDP1L3MBTL1 | |
| SCHEMBL9305444 | 0.74 | ITGB1 (0.66) | ALDH1A1ITGB1ITGA4TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5334730-A | Amidation with an 2-aminocarboxylic acid ester, cleavage the amide bond, solvent extraction to isolate | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1994-08-02 | — | — | US | disclosed |