Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.63 |
| ▸ | HTR2C | P28335 | 1/20 | 0.63 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.60 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.60 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2260014 | 0.88 | HTR2A (0.65) | HTR2AHTR2CMTNR1AMTNR1BMCL1 | |
| SCHEMBL12572732 | 0.86 | HTR2A (0.60) | HTR2AHTR2CMTNR1AMTNR1BMCL1 | |
| SCHEMBL1395857 | 0.84 | MTNR1A (0.61) | HTR2AHTR2CMTNR1AMTNR1BMCL1 | |
| SCHEMBL6327455 | 0.84 | HTR2A (0.60) | HTR2AHTR2CMTNR1AMTNR1BMCL1 | |
| SCHEMBL12312046 | 0.83 | HTR2A (0.59) | HTR2AHTR2CMTNR1AMTNR1BMCL1 | |
| SCHEMBL15024522 | 0.82 | HTR2A (0.69) | HTR2AHTR2CMTNR1AMTNR1BMCL1 | |
| SCHEMBL27977246 | 0.82 | HTR2A (0.57) | HTR2AHTR2CMTNR1AMTNR1BMCL1 | |
| SCHEMBL1395799 | 0.81 | HTR2A (0.52) | HTR2AHTR2CMTNR1AMTNR1BMCL1 | |
| SCHEMBL2345293 | 0.80 | HTR2A (0.70) | HTR2AHTR2CMTNR1AMTNR1BMCL1 | |
| SCHEMBL2020434 | 0.80 | MTNR1A (0.59) | HTR2AHTR2CMTNR1AMTNR1BMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5324725-A | Antiinflammatory agent, antiallergen | KALI-CHEMIE PHARMA GMBH (DE) | 1994-06-28 | — | — | US | disclosed |
| EP-0529452-A2 | 1,7-Condensed 2-(piperazinoalkyl)indol derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them | Kali-Chemie Pharma GmbH (DE) | 1993-03-03 | — | — | EP | disclosed |