Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 6/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.49 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.49 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303029 | 0.91 | PARP1 (0.52) | HPSEPARP1PARP10PARP15PARP14 | |
| SCHEMBL1185244 | 0.89 | KMT2A (0.58) | HPSEPARP1PARP10PARP15MEN1 | |
| Hydrochloric Acid SCHEMBL3839558 | 0.88 | KMT2A (0.57) | HPSEPARP1PARP10PARP15MEN1 | |
| Hydrochloric Acid SCHEMBL29568124 | 0.88 | KMT2A (0.57) | HPSEPARP1PARP10PARP15MEN1 | |
| SCHEMBL895690 | 0.85 | MEN1 (0.63) | PARP1PARP10PARP15PARP14MEN1 | |
| SCHEMBL9304038 | 0.83 | KMT2A (0.50) | HPSEPARP1PARP10PARP15MEN1 | |
| 4-Guanidino-Benzoic Acid SCHEMBL9303333 | 0.83 | F2 (0.61) | PARP10PARP15ITGB3ITGA2BPLAU | |
| Hydrochloric Acid SCHEMBL2546537 | 0.83 | MEN1 (0.61) | PARP1PARP10PARP15PARP14MEN1 | |
| 4-Guanidino-Benzoic Acid SCHEMBL9304265 | 0.83 | MEN1 (0.56) | HPSEMEN1KMT2AITGB3ITGA2B | |
| SCHEMBL7339507 | 0.82 | NPC1 (0.54) | HPSEMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352704-A | Antiviral agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0434432-B1 | Guanidinobenzene derivatives | BANYU PHARMA CO LTD (JP) | 1994-05-04 | — | — | EP | disclosed |
| EP-0434432-A1 | Guanidinobenzene derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-06-26 | — | — | EP | disclosed |