Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1185244 | 0.87 | KMT2A (0.58) | KMT2AMEN1RAB9ANPC1LMNA | |
| Hydrochloric Acid SCHEMBL3839558 | 0.85 | KMT2A (0.57) | KMT2AMEN1RAB9ANPC1LMNA | |
| Hydrochloric Acid SCHEMBL29568124 | 0.85 | KMT2A (0.57) | KMT2AMEN1RAB9ANPC1LMNA | |
| 4-Guanidino-Benzoic Acid SCHEMBL9303605 | 0.85 | PLAU (0.50) | KMT2AMEN1SIRT2 | |
| SCHEMBL9303029 | 0.83 | PARP1 (0.52) | KMT2AMEN1RAB9ANPC1HPSE | |
| SCHEMBL9303737 | 0.83 | HPSE (0.50) | KMT2AMEN1RAB9ANPC1NR1H4 | |
| SCHEMBL7339507 | 0.80 | NPC1 (0.54) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL895690 | 0.79 | MEN1 (0.63) | KMT2AMEN1PARP1PARP15PARP10 | |
| SCHEMBL9304048 | 0.78 | SIRT2 (0.55) | KMT2AMEN1SIRT2NR1H4 | |
| SCHEMBL5354517 | 0.78 | L3MBTL1 (0.60) | KMT2AMEN1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352704-A | Antiviral agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0434432-B1 | Guanidinobenzene derivatives | BANYU PHARMA CO LTD (JP) | 1994-05-04 | — | — | EP | disclosed |
| EP-0434432-A1 | Guanidinobenzene derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-06-26 | — | — | EP | disclosed |