Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | CES2 | O00748 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13754160 | 1.00 | CES1 (0.55) | CES1TSHRLMNACES2ALDH1A1 | |
| SCHEMBL11171387 | 0.94 | CES1 (0.58) | CES1TSHRLMNACES2ALDH1A1 | |
| SCHEMBL9302512 | 0.93 | CES1 (0.63) | CES1TSHRLMNACES2ALDH1A1 | |
| SCHEMBL9303099 | 0.92 | CES1 (0.50) | CES1TSHRLMNACES2ALDH1A1 | |
| SCHEMBL9860776 | 0.89 | CES1 (0.64) | CES1TSHRLMNACES2ALDH1A1 | |
| SCHEMBL10609830 | 0.84 | TSHR (0.44) | CES1TSHRLMNACES2ALDH1A1 | |
| SCHEMBL1470605 | 0.84 | TSHR (0.44) | CES1TSHRLMNACES2ALDH1A1 | |
| SCHEMBL11084666 | 0.84 | CES1 (0.53) | CES1ALDH1A1MAPK1 | |
| SCHEMBL11768405 | 0.84 | CES1 (0.45) | CES1TSHRLMNACES2ALDH1A1 | |
| SCHEMBL11083597 | 0.82 | CES1 (0.54) | CES1LMNAALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5288917-A | Benzil ketals; end-capped polyoxyyethylene glycol; mixed with titanocene-type initiators | CIBA-GEIGY CORPORATION (US) | 1994-02-22 | — | — | US | disclosed |
| EP-0242330-B1 | LIQUID BLEND OF PHOTOINITIATORS | CIBA-GEIGY AG (CH) | 1990-05-16 | — | — | EP | disclosed |
| EP-0242330-A1 | Liquid blend of photoinitiators | CIBA-GEIGY AG (CH) | 1987-10-21 | — | — | EP | disclosed |