Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13754160 | 0.92 | CES1 (0.55) | CES1TSHRCES2LMNAALDH1A1 | |
| SCHEMBL9303826 | 0.92 | CES1 (0.55) | CES1TSHRCES2LMNAALDH1A1 | |
| SCHEMBL9785921 | 0.86 | CES1 (0.55) | CES1LMNAALDH1A1CYP3A4MAPK1 | |
| SCHEMBL11171387 | 0.86 | CES1 (0.58) | CES1TSHRCES2LMNAALDH1A1 | |
| SCHEMBL9302512 | 0.85 | CES1 (0.63) | CES1TSHRCES2LMNAALDH1A1 | |
| SCHEMBL9785847 | 0.85 | CES1 (0.57) | CES1CES2LMNAALDH1A1KCNH2 | |
| SCHEMBL9860776 | 0.84 | CES1 (0.64) | CES1TSHRCES2LMNAALDH1A1 | |
| SCHEMBL9785859 | 0.83 | CES1 (0.59) | CES1TSHRLMNAALDH1A1 | |
| SCHEMBL3266492 | 0.79 | CES1 (0.65) | CES1TSHRLMNAALDH1A1 | |
| SCHEMBL11482930 | 0.77 | CES1 (0.51) | CES1TSHRCES2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5288917-A | Benzil ketals; end-capped polyoxyyethylene glycol; mixed with titanocene-type initiators | CIBA-GEIGY CORPORATION (US) | 1994-02-22 | — | — | US | disclosed |