Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9443205 | 0.92 | HPGD (0.46) | HPGDALDH1A1LMNANPC1RAB9A | |
| SCHEMBL9443217 | 0.91 | HPGD (0.45) | HPGDALDH1A1LMNANPC1RAB9A | |
| SCHEMBL9443210 | 0.84 | HPGD (0.45) | HPGDALDH1A1LMNANPC1RAB9A | |
| SCHEMBL9306573 | 0.82 | NPC1 (0.43) | HPGDALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9306676 | 0.81 | HDAC6 (0.46) | NPC1RAB9ASMN1; SMN2HDAC6 | |
| SCHEMBL9443213 | 0.79 | PPARA (0.54) | HPGDALDH1A1LMNA | |
| SCHEMBL9306485 | 0.76 | HPGD (0.57) | HPGDALDH1A1LMNANPC1RAB9A | |
| SCHEMBL8972937 | 0.76 | NPC1 (0.54) | HPGDALDH1A1LMNANPC1RAB9A | |
| SCHEMBL9734400 | 0.75 | HPGD (0.56) | HPGDALDH1A1LMNANPC1RAB9A | |
| SCHEMBL8972967 | 0.75 | NPC1 (0.52) | HPGDALDH1A1LMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |