Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 10/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734400 | 0.84 | HPGD (0.56) | HPGDALDH1A1LMNAHSP90AA1HSP90AB1 | |
| SCHEMBL9304903 | 0.77 | NPC1 (0.53) | HPGDALDH1A1LMNASMN1; SMN2NPC1 | |
| SCHEMBL25252536 | 0.77 | NPC1 (0.70) | HPGDALDH1A1LMNASMN1; SMN2NPC1 | |
| SCHEMBL30063475 | 0.77 | NPC1 (0.70) | HPGDALDH1A1LMNASMN1; SMN2NPC1 | |
| SCHEMBL9303830 | 0.76 | HPGD (0.47) | HPGDALDH1A1LMNAHSP90AA1HSP90AB1 | |
| SCHEMBL9443205 | 0.76 | HPGD (0.46) | HPGDALDH1A1LMNAHSP90AA1HSP90AB1 | |
| SCHEMBL9443217 | 0.75 | HPGD (0.45) | HPGDALDH1A1LMNAHSP90AA1HSP90AB1 | |
| SCHEMBL9443210 | 0.75 | HPGD (0.45) | HPGDALDH1A1LMNAHSP90AA1HSP90AB1 | |
| SCHEMBL31398710 | 0.75 | HDAC1 (0.51) | HPGDALDH1A1LMNAHSP90AA1SMN1; SMN2 | |
| SCHEMBL9443213 | 0.74 | PPARA (0.54) | HPGDALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0129506-B1 | HETEROCYCLICALLY SUBSTITUTED THIO(CYCLO)ALKANE POLYCARBOXYLIC ACIDS | CIBA-GEIGY AG (CH) | 1991-03-06 | — | — | EP | disclosed |
| EP-0129506-A2 | Heterocyclically substituted thio(cyclo)alkane polycarboxylic acids | CIBA-GEIGY AG (CH) | 1984-12-27 | — | — | EP | disclosed |