Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 9/20 | 0.60 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.60 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.44 |
| ▸ | SSTR5 | P35346 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MLNR | O43193 | 1/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.40 |
| ▸ | EED | O75530 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | HLA-A | P04439 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8162459 | 0.88 | SSTR5 (0.48) | KCNH2NR4A2SSTR5LMNAGAA | |
| Water SCHEMBL9302746 | 0.87 | KCNH2 (0.48) | KCNH2NR4A2SSTR5LMNAGAA | |
| Water SCHEMBL9303347 | 0.87 | KCNH2 (0.48) | KCNH2NR4A2SSTR5LMNAGAA | |
| Water SCHEMBL9303352 | 0.87 | KCNH2 (0.48) | KCNH2NR4A2SSTR5LMNAGAA | |
| Hydrochloric Acid SCHEMBL9303379 | 0.86 | KCNH2 (0.48) | KCNH2NR4A2SSTR5LMNAGAA | |
| SCHEMBL9697200 | 0.85 | KCNH2 (0.62) | KCNH2NR4A2SOS1SSTR5LMNA | |
| Hydrochloric Acid SCHEMBL9302235 | 0.85 | KCNH2 (0.57) | KCNH2NR4A2SOS1SSTR5LMNA | |
| Hydrochloric Acid SCHEMBL8567744 | 0.85 | KCNH2 (0.57) | KCNH2NR4A2SOS1SSTR5LMNA | |
| SCHEMBL9537073 | 0.85 | SSTR5 (0.51) | KCNH2NR4A2SSTR5LMNAGAA | |
| SCHEMBL7864978 | 0.84 | KCNH2 (0.45) | KCNH2NR4A2SSTR5LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5278165-A | Oxazolyl imidazol[4,5-b]pyridin and pyrimidine compounds | JANSSEN PHARMACEUTICA N.V. (BE) | 1994-01-11 | — | — | US | disclosed |
| US-5217980-A | Antiallergens | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-06-08 | — | — | US | disclosed |
| WO-1992001687-A1 | NOVEL OXAZOLYL DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-02-06 | — | — | WO | disclosed |