Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | DRD1 | P21728 | 2/20 | 0.43 |
| ▸ | HTR1B | P28222 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9304965 | 0.89 | HTR1A (0.54) | DRD2HTR1ADRD1HTR1BHTR2A | |
| SCHEMBL9305738 | 0.82 | HTR1A (0.47) | DRD2HTR1ADRD1HTR1BHTR2A | |
| SCHEMBL9304340 | 0.81 | HTR1A (0.64) | DRD2HTR1ADRD1HTR1BHTR2A | |
| SCHEMBL9304956 | 0.72 | HTR1A (0.81) | DRD2HTR1ADRD1HTR1BHTR2A | |
| Oxalic Acid SCHEMBL9304567 | 0.70 | HTR1A (0.75) | DRD2HTR1ADRD1HTR1BHTR2A | |
| SCHEMBL9305474 | 0.69 | HTR1A (0.47) | DRD2HTR1ADRD1HTR1BHTR2A | |
| SCHEMBL9305493 | 0.68 | HTR1A (0.58) | DRD2HTR1ADRD1HTR1BHTR2A | |
| SCHEMBL9305392 | 0.68 | HTR1A (0.47) | DRD2HTR1ADRD1HTR1BHTR2A | |
| SCHEMBL9305727 | 0.65 | HTR1A (0.71) | DRD2HTR1ADRD1HTR1BHTR2A | |
| SCHEMBL9304624 | 0.64 | HTR1A (0.41) | DRD2HTR1ADRD1HTR1BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5346916-A | FOR TREATING ANIMALS SUFFERING FROM DISORDERS OF THE SEROTONINERGIC SYSTEM | ADIR ET COMPAGNIE (FR) | 1994-09-13 | — | — | US | disclosed |
| US-5273994-A | Also hydroxy- or alkyl ether-substituted | ADIR ET COMPAGNIE (FR) | 1993-12-28 | — | — | US | disclosed |