Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.72 |
| ▸ | DRD2 | P14416 | 1/20 | 0.72 |
| ▸ | DRD1 | P21728 | 1/20 | 0.72 |
| ▸ | HTR1B | P28222 | 1/20 | 0.72 |
| ▸ | HTR2A | P28223 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9306063 | 0.97 | HTR1A (0.68) | HTR1ADRD2DRD1HTR1BHTR2A | |
| SCHEMBL9305322 | 0.94 | HTR1A (0.62) | HTR1ADRD2DRD1HTR1BHTR2A | |
| SCHEMBL9305464 | 0.88 | HTR1A (0.72) | HTR1ADRD2DRD1HTR1BHTR2A | |
| SCHEMBL9306008 | 0.86 | HTR1A (0.83) | HTR1ADRD2DRD1HTR1BHTR2A | |
| Oxalic Acid SCHEMBL9307751 | 0.84 | HTR1A (0.67) | HTR1ADRD2DRD1HTR1BHTR2A | |
| Alnespirone SCHEMBL114478 | 0.84 | HTR1A (1.00) | HTR1ADRD2DRD1HTR1BHTR2A | |
| Alnespirone SCHEMBL13532499 | 0.84 | HTR1A (1.00) | HTR1ADRD2DRD1HTR1BHTR2A | |
| Alnespirone SCHEMBL29639699 | 0.84 | HTR1A (1.00) | HTR1ADRD2DRD1HTR1BHTR2A | |
| SCHEMBL2217080 | 0.83 | HTR1A (0.66) | HTR1ADRD2DRD1HTR1BHTR2A | |
| Alnespirone SCHEMBL114479 | 0.83 | HTR1A (0.98) | HTR1ADRD2DRD1HTR1BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5314907-A | 3-aminochroan compounds | ADIR ET COMPAGNIE (FR) | 1994-05-24 | — | — | US | claimed |
| US-5346916-A | FOR TREATING ANIMALS SUFFERING FROM DISORDERS OF THE SEROTONINERGIC SYSTEM | ADIR ET COMPAGNIE (FR) | 1994-09-13 | — | — | US | disclosed |
| US-5314907-A | 3-aminochroan compounds | ADIR ET COMPAGNIE (FR) | 1994-05-24 | — | — | US | disclosed |
| US-5273994-A | Also hydroxy- or alkyl ether-substituted | ADIR ET COMPAGNIE (FR) | 1993-12-28 | — | — | US | disclosed |