SCHEMBL9304826

SCHEMBL9304826

CCc1c(O)c(Cl)c(Cl)c(Cl)c1Cl

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.47
HPGD P15428 4/20 0.47
HSD17B10 Q99714 4/20 0.47
MEN1 O00255 2/20 0.47
LMNA P02545 2/20 0.47
MAPT P10636 2/20 0.47
KMT2A Q03164 2/20 0.47
ALDH1A1 P00352 1/20 0.47
CYP1A2 P05177 5/20 0.41
CYP2C9 P11712 4/20 0.41
HIF1A Q16665 4/20 0.41
MAPK1 P28482 3/20 0.41
CYP2C19 P33261 2/20 0.38
CYP3A4 P08684 2/20 0.34
NPC1 O15118 1/20 0.31
USP2 O75604 1/20 0.31
EGFR P00533 1/20 0.31
ESR1 P03372 1/20 0.31
ERBB2 P04626 1/20 0.31
LCK P06239 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5588038 0.92 TSHR (0.45) TSHRHPGDHSD17B10MEN1LMNA
SCHEMBL24040559 0.82 IMPDH2 (0.34) HPGDHSD17B10MEN1KMT2AALDH1A1
SCHEMBL5588710 0.81 TSHR (0.38) TSHRHPGDHSD17B10MEN1LMNA
SCHEMBL24462742 0.80 TSHR (0.39) TSHRHPGDHSD17B10MEN1LMNA
SCHEMBL3179716 0.78
SCHEMBL14274017 0.78
SCHEMBL23848687 0.77 SMN1; SMN2 (0.37) TSHRHPGDHSD17B10MEN1LMNA
SCHEMBL24462659 0.77
SCHEMBL9812505 0.77 TSHR (0.53) TSHRHPGDHSD17B10MEN1LMNA
SCHEMBL13625816 0.77 TSHR (0.53) TSHRHPGDHSD17B10MEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2653488-B1 POLYESTER COMPOSITION FOR SOLAR BATTERY AND METHOD FOR PRODUCING SAME TORAY INDUSTRIES (JP) 2018-10-03 EP claimed
US-10774178-B2 Polyethylene terephthalate resin composition and film formed from same TORAY INDUSTRIES, INC. (JP) 2020-09-15 US disclosed
EP-3369776-B1 POLYETHYLENE TEREPHTHALATE RESIN COMPOSITION AND FILM FORMED FROM SAME TORAY INDUSTRIES (JP) 2020-04-29 EP disclosed
US-20180319977-A1 POLYETHYLENE TEREPHTHALATE RESIN COMPOSITION AND FILM FORMED FROM SAME TORAY INDUSTRIES, INC. (JP) 2018-11-08 US disclosed
EP-2653488-B1 POLYESTER COMPOSITION FOR SOLAR BATTERY AND METHOD FOR PRODUCING SAME TORAY INDUSTRIES (JP) 2018-10-03 EP disclosed
EP-3369776-A1 POLYETHYLENE TEREPHTHALATE RESIN COMPOSITION AND FILM FORMED FROM SAME Toray Industries, Inc. (JP) 2018-09-05 EP disclosed
US-9169349-B2 Polyester composition for solar battery and method for producing same TORAY INDUSTRIES, INC. (JP) 2015-10-27 US disclosed
US-20130281635-A1 POLYESTER COMPOSITION FOR SOLAR BATTERY AND METHOD FOR PRODUCING SAME TORAY INDUSTRIES, INC (JP) 2013-10-24 US disclosed
EP-2653488-A1 POLYESTER COMPOSITION FOR SOLAR BATTERY AND METHOD FOR PRODUCING SAME Toray Industries, Inc. (JP) 2013-10-23 EP disclosed
US-5370929-A Heat treating polyethylene terephthalate with water or steam; degree of dye exhaustion improved; enhanced dyeing efficiency; deep color dyeing TORAY INDUSTRIES, INC. (JP) 1994-12-06 US disclosed
US-5296238-A Complex phosphate containing silver, zirconium or titanium, monovalent ion TOAGOSEI CHEMICAL INDUSTRY CO., INC. (JP) 1994-03-22 US disclosed
EP-0554709-A1 Polyester fiber, process for the production and process for the dyeing of the fibrous structure of the polyester fiber TORAY INDUSTRIES, INC. (JP) 1993-08-11 EP disclosed
US-4374031-A COATING FILAMENTS WITH LUBRICATING AGENT, SURFACTANT, EPOXY COMPOUND, BLOCKED ISOCYANATE, AND POLYOXYALKYLENE AMINE, AND HEATING UNITIKA LIMITED (JP) 1983-02-15 US disclosed