Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 20/20 | 0.83 |
| ▸ | ALOX5 | P09917 | 8/20 | 0.83 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303684 | 0.91 | ALOX5AP (1.00) | ALOX5APALOX5CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL169604 | 0.84 | PTGES2 (0.67) | ALOX5APALOX5CYP2C9CYP3A4 | |
| SCHEMBL30181651 | 0.84 | PTGES2 (0.67) | ALOX5APALOX5CYP2C9CYP3A4 | |
| SCHEMBL1192956 | 0.84 | ALOX5AP (0.81) | ALOX5APALOX5CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL9150053 | 0.83 | ALOX5AP (0.84) | ALOX5APALOX5CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL9254050 | 0.83 | ALOX5AP (0.63) | ALOX5APALOX5CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL1193638 | 0.83 | ALOX5AP (0.63) | ALOX5APALOX5CYP2C9CYP3A4 | |
| SCHEMBL3474765 | 0.82 | ALOX5AP (0.74) | ALOX5APALOX5CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL167199 | 0.82 | PTGES2 (0.66) | ALOX5APALOX5CYP2C9CYP3A4 | |
| SCHEMBL9178373 | 0.82 | ALOX5AP (0.86) | ALOX5APALOX5CYP2C9CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5288743-A | Lipoxygenase inhibitors | ABBOTT LABORATORIES (US) | 1994-02-22 | — | — | US | disclosed |