SCHEMBL9304982

SCHEMBL9304982

C=CCN1CNCNC1=O

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.38
GRIA1 P42261 1/20 0.33
GRIA2 P42262 1/20 0.33
GRIA3 P42263 1/20 0.33
GRIA4 P48058 1/20 0.33
POLB P06746 1/20 0.33
NPSR1 Q6W5P4 1/20 0.32
MAPT P10636 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3765643 0.75
Water SCHEMBL7155879 0.73 CYP3A4 (0.37) CYP3A4GRIA1GRIA2GRIA3GRIA4
SCHEMBL10977047 0.71 POLB (0.43) CYP3A4POLBMAPTL3MBTL1
SCHEMBL28883614 0.71 CYP3A4 (0.38) CYP3A4GRIA1GRIA2GRIA3GRIA4
SCHEMBL166418 0.70
SCHEMBL5139880 0.67
SCHEMBL5519257 0.67 CYP3A4 (0.42) CYP3A4GRIA1GRIA2GRIA3GRIA4
SCHEMBL14942906 0.67 CYP3A4 (0.42) CYP3A4GRIA1GRIA2GRIA3GRIA4
SCHEMBL11498881 0.67 GBA1 (0.38) CYP3A4MAPT
SCHEMBL6065457 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5300148-A Pigments, their production and use SANDOZ LTD. (CH) 1994-04-05 US disclosed