Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8972839 | 0.86 | SMN1; SMN2 (0.64) | SMN1; SMN2KMT2APOLBLMNAALDH1A1 | |
| SCHEMBL9305843 | 0.85 | SMN1; SMN2 (0.61) | SMN1; SMN2KMT2APOLBLMNAALDH1A1 | |
| SCHEMBL8972983 | 0.84 | SMN1; SMN2 (0.60) | SMN1; SMN2KMT2APOLBLMNARAB9A | |
| SCHEMBL10867320 | 0.84 | SMN1; SMN2 (0.60) | SMN1; SMN2KMT2APOLBLMNAALDH1A1 | |
| SCHEMBL8972735 | 0.80 | SMN1; SMN2 (0.72) | SMN1; SMN2KMT2APOLBLMNAALDH1A1 | |
| SCHEMBL10872581 | 0.77 | POLB (0.70) | SMN1; SMN2KMT2APOLBLMNAALDH1A1 | |
| SCHEMBL10866550 | 0.77 | SMN1; SMN2 (0.54) | SMN1; SMN2KMT2APOLBLMNAALDH1A1 | |
| SCHEMBL10640951 | 0.76 | SMN1; SMN2 (0.56) | SMN1; SMN2KMT2APOLBLMNARAB9A | |
| SCHEMBL757400 | 0.76 | KMT2A (0.67) | SMN1; SMN2KMT2APOLBLMNAALDH1A1 | |
| SCHEMBL11019032 | 0.76 | SMN1; SMN2 (0.66) | SMN1; SMN2KMT2APOLBLMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| US-4612049-A | BENZOTHI ZOLYL THIO-, BENZIMIDAZOLYLTHIO- OR BENZOXAZOLYLTHIO-SUBSTITUTED CARBOXY ACID | CIBA-GEIGY CORPORATION (US) | 1986-09-16 | — | — | US | disclosed |
| EP-0183647-A1 | Anti-corrosive aqueous paints | CIBA-GEIGY AG (CH) | 1986-06-04 | — | — | EP | disclosed |
| EP-0129506-A2 | Heterocyclically substituted thio(cyclo)alkane polycarboxylic acids | CIBA-GEIGY AG (CH) | 1984-12-27 | — | — | EP | disclosed |