Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9305326 | 1.00 | HSP90AA1 (0.41) | HSP90AA1HSP90AB1NAMPTALDH1A1SMN1; SMN2 | |
| SCHEMBL28180575 | 0.71 | CYP1A2 (0.36) | ALDH1A1LMNARAB9AKDM4EMAPT | |
| Benzene SCHEMBL28903623 | 0.67 | — | — | |
| SCHEMBL16095460 | 0.63 | ALDH1A1 (0.46) | HSP90AA1HSP90AB1NAMPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9305329 | 0.63 | HSP90AA1 (0.45) | HSP90AA1HSP90AB1NAMPTALDH1A1SMN1; SMN2 | |
| SCHEMBL1310396 | 0.63 | ALDH1A1 (0.46) | HSP90AA1HSP90AB1NAMPTALDH1A1SMN1; SMN2 | |
| SCHEMBL27534398 | 0.61 | NAMPT (0.49) | HSP90AA1HSP90AB1NAMPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9306054 | 0.61 | ALDH1A1 (0.37) | HSP90AA1HSP90AB1NAMPTALDH1A1SMN1; SMN2 | |
| SCHEMBL2639737 | 0.61 | — | — | |
| SCHEMBL223592 | 0.60 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2LMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374701-A | Crosslinkable polymers of high strength free of structural defects | HAY ALLAN S (CA) | 1994-12-20 | — | — | US | disclosed |
| US-5233046-A | DIARYLACETYLENES, ENAMINES AND ACETYLENIC POLYMERS AND THEIR PRODUCTION | HAY ALLAN S (CA) | 1993-08-03 | — | — | US | disclosed |
| WO-1993009079-A1 | DIARYLACETYLENES, ENAMINES AND ACETYLENIC POLYMERS AND THEIR PRODUCTION | HAY ALAN S (CA) | 1993-05-13 | — | — | WO | disclosed |