Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10435760 | 0.89 | HTT (0.43) | HTTALDH1A1TSHRFGFR4MAPT | |
| SCHEMBL623307 | 0.80 | — | — | |
| SCHEMBL10771737 | 0.80 | HTT (0.42) | HTTALDH1A1TSHRFGFR4MAPT | |
| SCHEMBL8668364 | 0.78 | — | — | |
| SCHEMBL28280664 | 0.78 | — | — | |
| SCHEMBL528085 | 0.77 | TSHR (0.42) | HTTALDH1A1TSHRMAPT | |
| SCHEMBL24882659 | 0.76 | — | — | |
| SCHEMBL175495 | 0.74 | HTT (0.45) | HTTALDH1A1TSHRFGFR4 | |
| SCHEMBL1640508 | 0.74 | HTT (0.45) | HTTALDH1A1TSHRFGFR4 | |
| SCHEMBL7703176 | 0.73 | HTT (0.38) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417870-B1 | Chelates for complexation of radioactive isotopes, their metal complexes and their use in diagnosis and therapy | DIAGNOSTIKFORSCHUNG INST (DE) | 1994-07-20 | — | — | EP | disclosed |
| US-5302370-A | Form complexes with rhenium and technetium | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH (DE) | 1994-04-12 | — | — | US | disclosed |
| EP-0417870-A2 | Chelates for complexation of radioactive isotopes, their metal complexes and their use in diagnosis and therapy | INSTITUT FÜR DIAGNOSTIKFORSCHUNG GmbH AN DER FREIEN UNIVERSITÄT BERLIN (DE) | 1991-03-20 | — | — | EP | disclosed |