SCHEMBL623307

SCHEMBL623307

C=CCC(C)(C)C(N)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28147328 0.89 HTT (0.37)
SCHEMBL9305418 0.80 HTT (0.42)
SCHEMBL10771737 0.80 HTT (0.42)
SCHEMBL4453702 0.79 CCR2 (0.36)
SCHEMBL1640508 0.79 HTT (0.45)
SCHEMBL8668364 0.78
SCHEMBL28280664 0.78
SCHEMBL28318567 0.78 HTT (0.34)
SCHEMBL4721831 0.77
SCHEMBL4161099 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1377589-B1 OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS PHARMACIA ITALIA SPA (IT) 2005-09-07 EP claimed
EP-4317222-A1 (METH)ACRYLIC ACID ESTER-BASED COPOLYMER AND CURABLE COMPOSITION Kaneka Corporation (JP) 2024-02-07 EP disclosed
CN-116606393-A Amphiphilic compound, and medical resin composition and drug additive each comprising the same 株式会社日本触媒 2023-08-18 CN disclosed
CN-116589702-A Amphiphilic compound, and medical resin composition and drug additive each comprising the same 株式会社日本触媒 2023-08-15 CN disclosed
CN-113646341-B Amphiphilic compound, and medical resin composition and drug additive each comprising the same 株式会社日本触媒 2023-04-18 CN disclosed
CN-107614568-B Fluoropolymer resin with formula 1 or formula 2, the then film containing it and the display device that is connected by then film 三星SDI株式会社 2019-06-11 CN disclosed
CN-107614568-A Macromolecule resin with chemical formula 1 or chemical formula 2, the then film containing it and the display device connected by then film 三星SDI株式会社 2018-01-19 CN disclosed
WO-2017193326-A1 DEGRADABLE VINYLPYRROLIDONE HOMOPOLYMERS AND COPOLYMERS AND METHODS FOR PREPARING THE SAME BOAI NKY PHARMACEUTICALS LTD. (CN) 2017-11-16 WO disclosed
CN-106687198-A Hygroscopic material and dehumidifier using same 夏普株式会社 2017-05-17 CN disclosed
US-8242103-B2 Sulphamides for treatment of cancer MERCK SHARP & DOHME LIMITED (GB) 2012-08-14 US disclosed
EP-1334085-B1 SULFAMIDES AS GAMMA-SECRETASE INHIBITORS MERCK SHARP & DOHME (GB) 2005-08-24 EP disclosed
US-20040049038-A1 Sulfamides as gamma-secretase inhibitors MERCK SHARP & DOHME (UK) LIMITED (GB) 2004-03-11 US disclosed
US-20040029862-A1 Sulphonamido-substituted bridged bicycloalkyl derivatives MERCK CANADA INC. (CA) 2004-02-12 US disclosed
EP-1377589-A1 OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS Pharmacia Italia S.p.A. (IT) 2004-01-07 EP disclosed
EP-1334085-A1 SULFAMIDES AS GAMMA-SECRETASE INHIBITORS MERCK SHARP & DOHME LTD. (GB) 2003-08-13 EP disclosed
EP-1268412-A1 SULPHONAMIDO-SUBSTITUTED BRIDGED BICYCLOALKYL DERIVATIVES MERCK SHARP &amp; DOHME LTD. (GB) 2003-01-02 EP disclosed
WO-2002062804-A1 OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS PHARMACIA ITALIA S.P.A. (IT) 2002-08-15 WO disclosed
WO-2002036555-A1 SULFAMIDES AS GAMMA-SECRETASE INHIBITORS MERCK SHARP & DOHME LIMITED (GB) 2002-05-10 WO disclosed
WO-2001091717-A1 ORAL DELIVERY FORM COMPRISING GLIPIZIDE ADD ADVANCED DRUG DELIVERY TECHNOLOGIES AG (CH) 2001-12-06 WO disclosed
WO-2001070677-A1 SULPHONAMIDO-SUBSTITUTED BRIDGED BICYCLOALKYL DERIVATIVES MERCK SHARP & DOHME LIMITED (GB) 2001-09-27 WO disclosed