Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 2/20 | 0.62 |
| ▸ | MAOA | P21397 | 2/20 | 0.60 |
| ▸ | MAOB | P27338 | 1/20 | 0.60 |
| ▸ | PTPRC | P08575 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.49 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.49 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29400632 | 0.87 | S100A4 (0.66) | S100A4MAOAPTPRCCA2CA9 | |
| SCHEMBL2205543 | 0.87 | S100A4 (0.66) | S100A4MAOAPTPRCCA2CA9 | |
| SCHEMBL8777750 | 0.85 | S100A4 (0.68) | S100A4MAOAPTPRCCA2CA9 | |
| SCHEMBL2347136 | 0.85 | S100A4 (0.84) | S100A4PTPRCCA2CA9CA1 | |
| SCHEMBL11317413 | 0.81 | S100A4 (0.78) | S100A4PTPRCCA2CA9CA1 | |
| SCHEMBL10813560 | 0.81 | S100A4 (0.66) | S100A4MAOBPTPRCCA2CA9 | |
| SCHEMBL11515836 | 0.80 | S100A4 (0.60) | S100A4PTPRCCA2CA9CA1 | |
| SCHEMBL11210972 | 0.80 | S100A4 (0.75) | S100A4PTPRCCA2CA9CA1 | |
| Anthraquinone SCHEMBL27736010 | 0.80 | S100A4 (0.79) | S100A4MAOBPTPRCCA2CA9 | |
| SCHEMBL156735 | 0.80 | S100A4 (0.79) | S100A4MAOBPTPRCCA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0613366-A1 | 5,6-DIHYDROXYINDOLINE AS ADDITIVES FOR HAIR-DYEING PREPARATIONS. | HENKEL KGAA (DE) | 1994-09-07 | — | — | EP | disclosed |
| WO-1993009759-A1 | 5,6-DIHYDROXYINDOLINE AS ADDITIVES FOR HAIR-DYEING PREPARATIONS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1993-05-27 | — | — | WO | disclosed |