Iodide

Iodide

SCHEMBL9305626

CCCCCCCCCCCCCCOc1ccc(N(Cc2cccc[n+]2CCC)C(C)=O)cc1C(C)(C)C.[I-]

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG

The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.44
THRB P10828 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL9308226 1.00 THRA (0.44) THRATHRB
Iodide SCHEMBL9307264 0.89 THRA (0.46) THRATHRB
Iodide SCHEMBL9305759 0.88 THRA (0.42) THRATHRB
Iodide SCHEMBL9306908 0.88 THRA (0.42) THRATHRB
Iodide SCHEMBL9308172 0.84 THRA (0.46) THRATHRB
Iodide SCHEMBL9308451 0.84 THRA (0.49) THRATHRB
Iodide SCHEMBL9307913 0.84 THRA (0.49) THRATHRB
Iodide SCHEMBL9309002 0.82
Iodide SCHEMBL9304938 0.81
Iodide SCHEMBL9307738 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5328921-A Antagonist of platelet activating factor AMERICAN CYANAMID COMPANY (US) 1994-07-12 US disclosed