Benzophenone

Benzophenone

SCHEMBL9305650

COCCOC.O=C(c1ccccc1)c1ccccc1

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.64
L3MBTL1 Q9Y468 3/20 0.54
ATM Q13315 2/20 0.54
TDP1 Q9NUW8 2/20 0.54
SRD5A2 P31213 1/20 0.54
TSHR P16473 2/20 0.53
ELANE P08246 2/20 0.53
GAA P10253 1/20 0.53
HPGD P15428 4/20 0.53
LMNA P02545 3/20 0.53
MAPT P10636 2/20 0.53
CA2 P00918 1/20 0.52
POLB P06746 2/20 0.50
RAB9A P51151 2/20 0.50
NPC1 O15118 1/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
CYP1A2 P05177 1/20 0.49
CYP2D6 P10635 1/20 0.49
CYP2C19 P33261 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7266961 0.87 MAPT (0.72) ALDH1A1L3MBTL1ELANEGAALMNA
Benzophenone SCHEMBL2955921 0.85 ALDH1A1 (0.78) ALDH1A1L3MBTL1ATMTDP1SRD5A2
SCHEMBL28419696 0.85 PPARG (0.56) ALDH1A1L3MBTL1ATMSRD5A2ELANE
SCHEMBL11472938 0.84 ATM (0.57) ALDH1A1L3MBTL1ATMSRD5A2ELANE
Benzophenone SCHEMBL11655436 0.83 ALDH1A1 (0.74) ALDH1A1L3MBTL1ATMTDP1SRD5A2
SCHEMBL20537075 0.83 LIG1 (0.58) ALDH1A1TDP1TSHRGAAHPGD
SCHEMBL11306459 0.82 ALDH1A1 (0.50) ALDH1A1L3MBTL1ATMSRD5A2ELANE
SCHEMBL10942972 0.82 PPARA (0.46) ALDH1A1L3MBTL1ATMSRD5A2ELANE
SCHEMBL514995 0.81 TSHR (0.69) ALDH1A1TDP1TSHRLMNAMAPT
Benzophenone SCHEMBL8089683 0.80 ALDH1A1 (0.78) ALDH1A1L3MBTL1ATMTDP1SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5331103-A Reaction with hydrogen peroxide, hydroquinone from phenol RHONE-POULENC CHIMIE (FR) 1994-07-19 US disclosed
US-4749514-A INSERTED BETWEEN AROMATIC LAYERS OF HEAT TREATED GRAPHITIZED POLYPHENYLENEOXADIAZOLE RESEARCH DEVELOPMENT CORP. OF JAPAN (JP) 1988-06-07 US disclosed
EP-0223047-A2 Graphite intercalation compound film and method of preparing the same Research Development Corporation of Japan (JP) 1987-05-27 EP disclosed