SCHEMBL9305680

SCHEMBL9305680

CN(C)CC(=O)CCC(=O)CN(C)C

nearest known ligand 0.33

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ACE P12821 1/20 0.33
LMNA P02545 1/20 0.33
ALDH1A1 P00352 4/20 0.32
KDM4E B2RXH2 2/20 0.32
EGFR P00533 2/20 0.32
USP2 O75604 1/20 0.32
CHRM1 P11229 1/20 0.32
PHF8 Q9UPP1 2/20 0.32
KDM2A Q9Y2K7 2/20 0.32
KDM6B O15054 1/20 0.32
KDM5C P41229 1/20 0.32
EGLN1 Q9GZT9 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17884489 0.89 ACE (0.50) ACELMNAALDH1A1KDM4EPHF8
SCHEMBL10669712 0.89 ALDH1A1 (0.53) LMNAALDH1A1KDM4ECHRM1PHF8
SCHEMBL2111443 0.86 TDP1 (0.35) LMNAALDH1A1KDM4EEGFRUSP2
SCHEMBL6701745 0.85
SCHEMBL19759003 0.83 TSHR (0.59) LMNAALDH1A1KDM4EPHF8KDM2A
SCHEMBL15627459 0.81 CAMK2A (0.42) LMNAALDH1A1KDM4E
SCHEMBL3671115 0.81 ALDH1A1 (0.52) ALDH1A1TDP1KMT2ATSHR
SCHEMBL6704974 0.80 EGFR (0.32) ALDH1A1KDM4EEGFRUSP2TDP1
SCHEMBL15813390 0.79 ALDH1A1 (0.50) ALDH1A1TDP1KMT2ATSHR
SCHEMBL13672687 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5352833-A Microbiocide ISP INVESTMENTS INC. (US) 1994-10-04 US disclosed
WO-1994009768-A1 ANTIBACTERIAL POLYMERIC QUATERNARY AMMONIUM COMPOUNDS ISP INVESTMENTS INC. (US) 1994-05-11 WO disclosed