⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14503179 | 0.82 | — | — | |
| SCHEMBL10793567 | 0.82 | — | — | |
| SCHEMBL789937 | 0.82 | — | — | |
| SCHEMBL37610 | 0.82 | — | — | |
| SCHEMBL2107487 | 0.82 | — | — | |
| SCHEMBL29160979 | 0.82 | — | — | |
| SCHEMBL19286705 | 0.80 | — | — | |
| SCHEMBL7505215 | 0.79 | TRPV1 (0.40) | — | |
| Isopropyl Alcohol SCHEMBL9220560 | 0.78 | ALDH1A1 (0.55) | — | |
| Ammonia Solution, Strong SCHEMBL27642939 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0495265-B1 | Acid-labile linker molecules | AKZO NOBEL NV (NL) | 1994-08-03 | — | — | EP | disclosed |
| US-5306809-A | Cancer immune therapy | AKZO N.V. (NL) | 1994-04-26 | — | — | US | disclosed |
| EP-0354819-B1 | Novel peptide and anti-dementia agent | NIPPON CHEMIPHAR CO (JP) | 1994-04-13 | — | — | EP | disclosed |
| US-5180712-A | Alzheimer's disease | FUJIREBIO KABUSHIKI KAISHA (JP) | 1993-01-19 | — | — | US | disclosed |
| EP-0495265-A1 | Acid-labile linker molecules | Akzo Nobel N.V. (NL) | 1992-07-22 | — | — | EP | disclosed |
| EP-0354819-A2 | Novel peptide and anti-dementia agent | NIPPON CHEMIPHAR CO., LTD. (JP) | 1990-02-14 | — | — | EP | disclosed |