Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 11/20 | 0.72 |
| ▸ | RAB9A | P51151 | 11/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | LCK | P06239 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1748004 | 0.81 | SMN1; SMN2 (0.63) | NPC1RAB9AALDH1A1LMNALCK | |
| SCHEMBL1036069 | 0.79 | KDM4E (0.62) | NPC1RAB9AALDH1A1LMNAHTT | |
| SCHEMBL5757247 | 0.79 | NPC1 (0.65) | NPC1RAB9AALDH1A1LMNAHTT | |
| SCHEMBL14807050 | 0.79 | HTT (0.79) | NPC1RAB9AALDH1A1LMNAHTT | |
| Hydrochloric Acid SCHEMBL7753018 | 0.78 | KDM4E (0.60) | NPC1RAB9AALDH1A1LMNAHTT | |
| SCHEMBL10759303 | 0.78 | NPC1 (0.63) | NPC1RAB9AALDH1A1LMNAHTT | |
| SCHEMBL31469985 | 0.78 | RAB9A (0.51) | NPC1RAB9AALDH1A1LMNAHTT | |
| SCHEMBL5534541 | 0.77 | HTT (1.00) | NPC1RAB9AALDH1A1LMNAHTT | |
| SCHEMBL1095256 | 0.76 | SMN1; SMN2 (0.46) | NPC1RAB9AALDH1A1LMNAMAPT | |
| SCHEMBL7452674 | 0.76 | RAB9A (0.65) | NPC1RAB9AALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |