Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL9305575 | 0.91 | THRA (0.42) | THRATHRB | |
| Iodide SCHEMBL9307912 | 0.91 | THRA (0.42) | THRATHRB | |
| Iodide SCHEMBL9307714 | 0.89 | THRA (0.45) | THRATHRB | |
| Iodide SCHEMBL9307599 | 0.89 | ATM (0.44) | THRATHRB | |
| Iodide SCHEMBL9307363 | 0.87 | THRA (0.45) | THRATHRB | |
| Iodide SCHEMBL9308615 | 0.85 | THRA (0.45) | THRATHRB | |
| Iodide SCHEMBL9307023 | 0.84 | TP53 (0.42) | — | |
| Iodide SCHEMBL9306559 | 0.83 | THRA (0.43) | THRATHRB | |
| Iodide SCHEMBL9307691 | 0.81 | ATM (0.43) | THRATHRB | |
| Iodide SCHEMBL9305255 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5328921-A | Antagonist of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1994-07-12 | — | — | US | disclosed |