SCHEMBL9305926

SCHEMBL9305926

CC(C)(C(=O)O)C(I)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
TSHR P16473 2/20 0.38
MAPT P10636 1/20 0.33
PTGS1 P23219 1/20 0.33
TP53 P04637 1/20 0.32
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8038677 0.77
SCHEMBL2784195 0.77
SCHEMBL27877489 0.76 ALDH1A1 (0.36) ALDH1A1TSHRMAPTPTGS1TP53
SCHEMBL1558115 0.74
SCHEMBL18927583 0.72
SCHEMBL2518338 0.69 CPT2 (0.41) ALDH1A1TSHRMAPTPTGS1TP53
SCHEMBL15658875 0.69 CPT2 (0.41) ALDH1A1TSHRMAPTPTGS1TP53
SCHEMBL7326571 0.69 ALDH1A1 (0.40) ALDH1A1TSHRMAPTPTGS1TP53
SCHEMBL537269 0.69 CPT2 (0.41) ALDH1A1TSHRMAPTPTGS1TP53
SCHEMBL2784566 0.69 ALDH1A1 (0.40) ALDH1A1TSHRMAPTPTGS1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5347008-A Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents CIBA-GEIGY CORPORATION (US) 1994-09-13 US disclosed
US-5152929-A Corrosion inhibitors for water systems CIBA-GEIGY CORPORATION (US) 1992-10-06 US disclosed