Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.59 |
| ▸ | HTR2C | P28335 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | BCL2 | P10415 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9304934 | 0.96 | HTR2A (0.55) | HTR2AHTR2CKMT2AMEN1MAPK1 | |
| SCHEMBL9303008 | 0.90 | MCL1 (0.54) | HTR2AHTR2CKMT2AMEN1MAPK1 | |
| SCHEMBL17686297 | 0.88 | MCL1 (0.52) | HTR2AHTR2CKMT2AMEN1MAPK1 | |
| SCHEMBL17686287 | 0.87 | MCL1 (0.63) | HTR2AHTR2CKMT2AMEN1MAPK1 | |
| SCHEMBL8554628 | 0.85 | HTR2A (0.64) | HTR2AHTR2CKMT2AMEN1MAPK1 | |
| SCHEMBL8556575 | 0.81 | HTR2A (0.60) | HTR2AHTR2CKMT2AMEN1MCL1 | |
| SCHEMBL9303580 | 0.81 | MAPK1 (0.56) | HTR2AHTR2CKMT2AMEN1MAPK1 | |
| SCHEMBL9302647 | 0.81 | MAPK1 (0.55) | HTR2AHTR2CKMT2AMEN1MAPK1 | |
| SCHEMBL8552561 | 0.81 | MCL1 (0.57) | HTR2AHTR2CKMT2AMEN1MAPK1 | |
| SCHEMBL17686291 | 0.79 | MCL1 (0.50) | HTR2AHTR2CKMT2AMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5324725-A | Antiinflammatory agent, antiallergen | KALI-CHEMIE PHARMA GMBH (DE) | 1994-06-28 | — | — | US | disclosed |