Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | BCL2 | P10415 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17686297 | 0.94 | MCL1 (0.52) | MCL1KDM4EBCL2L1BCL2KMT2A | |
| SCHEMBL8552561 | 0.91 | MCL1 (0.57) | MCL1KDM4EBCL2L1BCL2KMT2A | |
| SCHEMBL17686287 | 0.91 | MCL1 (0.63) | MCL1KDM4EBCL2L1BCL2KMT2A | |
| SCHEMBL9305955 | 0.90 | HTR2A (0.59) | MCL1KDM4EBCL2L1BCL2KMT2A | |
| SCHEMBL9304934 | 0.86 | HTR2A (0.55) | MCL1KDM4EBCL2L1BCL2KMT2A | |
| SCHEMBL17686291 | 0.83 | MCL1 (0.50) | MCL1KDM4EBCL2L1BCL2KMT2A | |
| SCHEMBL17686350 | 0.81 | MCL1 (0.62) | MCL1KDM4EBCL2L1BCL2KMT2A | |
| SCHEMBL9304984 | 0.78 | ALOX5 (0.45) | MCL1KDM4EBCL2L1BCL2KMT2A | |
| SCHEMBL17686338 | 0.76 | MCL1 (0.56) | MCL1KDM4EBCL2L1BCL2KMT2A | |
| SCHEMBL17686307 | 0.75 | MCL1 (0.53) | MCL1KDM4EBCL2L1BCL2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5324725-A | Antiinflammatory agent, antiallergen | KALI-CHEMIE PHARMA GMBH (DE) | 1994-06-28 | — | — | US | disclosed |