Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 4/20 | 0.57 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP12 | P39900 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | MMP14 | P50281 | 1/20 | 0.48 |
| ▸ | ACP3 | P15309 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9305336 | 0.94 | FDFT1 (0.51) | FDFT1MMP2MMP9MMP12MMP13 | |
| SCHEMBL9303472 | 0.88 | RARB (0.48) | FDFT1 | |
| SCHEMBL15302634 | 0.86 | S1PR2 (0.57) | ACP3HDAC2HDAC1 | |
| SCHEMBL9544118 | 0.83 | FDFT1 (0.71) | FDFT1MMP2MMP9MMP12MMP13 | |
| SCHEMBL9417635 | 0.81 | FDFT1 (0.50) | FDFT1MMP12MME | |
| SCHEMBL23752399 | 0.78 | FDFT1 (0.60) | FDFT1ACP3 | |
| SCHEMBL10106389 | 0.78 | FDFT1 (0.64) | FDFT1MMP2MMP9MMP12MMP13 | |
| SCHEMBL8946999 | 0.78 | FDFT1 (0.60) | FDFT1ACP3 | |
| SCHEMBL8621199 | 0.78 | FDFT1 (0.60) | FDFT1ACP3 | |
| SCHEMBL24372481 | 0.77 | S1PR2 (0.57) | FDFT1ACP3FFAR1HDAC2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601573-A1 | Alpha-phosphonocarboxylate squalene synthetase inhibitors and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-06-15 | — | — | EP | claimed |
| EP-0601573-A1 | Alpha-phosphonocarboxylate squalene synthetase inhibitors and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-06-15 | — | — | EP | disclosed |
| US-5312814-A | Antilipemic agents or anticholesterol agents | BRISTOL-MYERS SQUIBB CO. (US) | 1994-05-17 | — | — | US | disclosed |