Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 4/20 | 0.50 |
| ▸ | MMP12 | P39900 | 2/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | EED | O75530 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4835745 | 0.84 | POLB (0.50) | POLB | |
| SCHEMBL6784313 | 0.82 | POLB (0.50) | POLB | |
| SCHEMBL8619955 | 0.81 | FDFT1 (0.53) | FDFT1POLB | |
| SCHEMBL9306035 | 0.81 | FDFT1 (0.57) | FDFT1MMP12MME | |
| SCHEMBL27872563 | 0.77 | POLB (0.43) | POLB | |
| SCHEMBL8622840 | 0.77 | FDFT1 (0.48) | FDFT1LPAR1 | |
| SCHEMBL9303472 | 0.76 | RARB (0.48) | FDFT1 | |
| SCHEMBL9305336 | 0.76 | FDFT1 (0.51) | FDFT1MMP12LPAR1 | |
| SCHEMBL7364336 | 0.75 | POLB (0.53) | POLB | |
| SCHEMBL4116935 | 0.75 | POLB (0.53) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601573-A1 | Alpha-phosphonocarboxylate squalene synthetase inhibitors and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-06-15 | — | — | EP | disclosed |