Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9306051 | 1.00 | HSP90AA1 (0.36) | HSP90AA1HSP90AB1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL19988107 | 0.65 | — | — | |
| SCHEMBL9306054 | 0.62 | ALDH1A1 (0.37) | HSP90AA1HSP90AB1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL8717437 | 0.62 | — | — | |
| SCHEMBL4799174 | 0.60 | KMT2A (0.35) | HSP90AA1HSP90AB1ALDH1A1MAPTNAMPT | |
| SCHEMBL18630376 | 0.59 | — | — | |
| SCHEMBL27534398 | 0.59 | NAMPT (0.49) | HSP90AA1HSP90AB1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL12809869 | 0.58 | ALDH1A1 (0.43) | HSP90AA1HSP90AB1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL13325913 | 0.58 | ALDH1A1 (0.43) | HSP90AA1HSP90AB1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL16199488 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374701-A | Crosslinkable polymers of high strength free of structural defects | HAY ALLAN S (CA) | 1994-12-20 | — | — | US | disclosed |
| US-5233046-A | DIARYLACETYLENES, ENAMINES AND ACETYLENIC POLYMERS AND THEIR PRODUCTION | HAY ALLAN S (CA) | 1993-08-03 | — | — | US | disclosed |
| WO-1993009079-A1 | DIARYLACETYLENES, ENAMINES AND ACETYLENIC POLYMERS AND THEIR PRODUCTION | HAY ALAN S (CA) | 1993-05-13 | — | — | WO | disclosed |