Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 11/20 | 0.44 |
| ▸ | RAB9A | P51151 | 10/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | STAT1 | P42224 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.41 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8972937 | 0.85 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL9306251 | 0.83 | NPC1 (0.43) | NPC1RAB9ASMN1; SMN2ALDH1A1STAT1 | |
| SCHEMBL9306245 | 0.83 | NPC1 (0.43) | NPC1RAB9ASMN1; SMN2ALDH1A1STAT1 | |
| SCHEMBL9443356 | 0.82 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2ALDH1A1STAT1 | |
| SCHEMBL9443205 | 0.82 | HPGD (0.46) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL8972523 | 0.82 | DYRK1A (0.46) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL9443179 | 0.82 | THRB (0.45) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9304878 | 0.79 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL10890582 | 0.78 | HRH3 (0.46) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL8973355 | 0.77 | PPARA (0.50) | SMN1; SMN2MAPTHSD17B10LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |