SCHEMBL9306307

SCHEMBL9306307

O=C(O)C(C(O)=S)c1nc2ccccc2s1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.58
CYP1A2 P05177 2/20 0.58
CYP2C19 P33261 2/20 0.58
CYP2C9 P11712 1/20 0.58
HIF1A Q16665 1/20 0.58
HSD17B10 Q99714 1/20 0.58
ALOX5 P09917 1/20 0.50
LOXL2 Q9Y4K0 1/20 0.46
RAB9A P51151 6/20 0.46
KMT2A Q03164 4/20 0.46
APEX1 P27695 1/20 0.45
CSNK1D P48730 1/20 0.44
NPC1 O15118 5/20 0.44
SMN1; SMN2 Q16637 5/20 0.44
MEN1 O00255 3/20 0.44
PKM P14618 2/20 0.44
MAPK1 P28482 2/20 0.44
NFKB1 P19838 2/20 0.44
NFKB2 Q00653 2/20 0.44
RELA Q04206 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9306300 0.90 HPGD (0.62) HPGDCYP1A2CYP2C19CYP2C9HIF1A
SCHEMBL1371913 0.88 HPGD (0.56) HPGDCYP1A2CYP2C19CYP2C9HIF1A
SCHEMBL11697365 0.85 HPGD (0.60) HPGDCYP1A2CYP2C19CYP2C9HIF1A
SCHEMBL9306298 0.84 HPGD (0.58) HPGDCYP1A2CYP2C19CYP2C9HIF1A
SCHEMBL5536307 0.80 HPGD (0.66) HPGDCYP1A2CYP2C19CYP2C9HIF1A
SCHEMBL30944811 0.79 PKM (0.52) HPGDCYP1A2CYP2C19CYP2C9HIF1A
SCHEMBL402777 0.79 PKM (0.52) HPGDCYP1A2CYP2C19CYP2C9HIF1A
SCHEMBL11191161 0.79 HPGD (0.60) HPGDCYP1A2CYP2C19CYP2C9HIF1A
SCHEMBL718297 0.79 HPGD (0.57) HPGDCYP1A2CYP2C19CYP2C9HIF1A
SCHEMBL3963337 0.79 HPGD (0.60) HPGDCYP1A2CYP2C19CYP2C9HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10669429-B2 Ambient cure compositions for making coatings having humidity and corrosion resistance and methods of use DOW GLOBAL TECHNOLOGIES LLC (US) 2020-06-02 US disclosed
US-20180371259-A1 AMBIENT CURE COMPOSITIONS FOR MAKING COATINGS HAVING HUMIDITY AND CORROSION RESISTANCE AND METHODS OF USE ROHM AND HAAS COMPANY 2018-12-27 US disclosed
US-10131813-B2 Ambient cure compositions for making coatings having humidity and corrosion resistance and methods of use DOW GLOBAL TECHNOLOGIES LLC (US) 2018-11-20 US disclosed
EP-3121235-B1 AMBIENT CURE COMPOSITIONS FOR MAKING COATINGS HAVING HUMIDITY AND CORROSION RESISTANCE AND METHODS OF USE DOW GLOBAL TECHNOLOGIES LLC (US) 2018-02-28 EP disclosed
US-20180022956-A1 AMBIENT CURE COMPOSITIONS FOR MAKING COATINGS HAVING HUMIDITY AND CORROSION RESISTANCE AND METHODS OF USE DOW GLOBAL TECHNOLOGIES LLC 2018-01-25 US disclosed
EP-3121235-A1 AMBIENT CURE COMPOSITIONS FOR MAKING COATINGS HAVING HUMIDITY AND CORROSION RESISTANCE AND METHODS OF USE Dow Global Technologies LLC (US) 2017-01-25 EP disclosed
US-5347008-A Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents CIBA-GEIGY CORPORATION (US) 1994-09-13 US disclosed
EP-0375614-B1 CORROSION-INHIBITING COATING COMPOSITIONS CIBA-GEIGY AG (CH) 1993-03-31 EP disclosed
US-5198482-A Benzothiazole carboxylic acid amine salt CIBA-GEIGY CORPORATION (US) 1993-03-30 US disclosed
US-5152929-A Corrosion inhibitors for water systems CIBA-GEIGY CORPORATION (US) 1992-10-06 US disclosed
EP-0375614-A1 Corrosion-inhibiting coating compositions CIBA-GEIGY AG (CH) 1990-06-27 EP disclosed
US-4612049-A BENZOTHI ZOLYL THIO-, BENZIMIDAZOLYLTHIO- OR BENZOXAZOLYLTHIO-SUBSTITUTED CARBOXY ACID CIBA-GEIGY CORPORATION (US) 1986-09-16 US disclosed