Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.68 |
| ▸ | THRB | P10828 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.59 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.59 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.58 |
| ▸ | RARB | P10826 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9626608 | 1.00 | THRA (0.68) | THRATHRBALDH1A1HPGDPTPN11 | |
| SCHEMBL9626804 | 1.00 | THRA (0.68) | THRATHRBALDH1A1HPGDPTPN11 | |
| SCHEMBL18682278 | 1.00 | THRA (0.68) | THRATHRBALDH1A1HPGDPTPN11 | |
| SCHEMBL11315317 | 1.00 | THRA (0.68) | THRATHRBALDH1A1HPGDPTPN11 | |
| SCHEMBL5348150 | 1.00 | THRA (0.68) | THRATHRBALDH1A1HPGDPTPN11 | |
| Hydrochloric Acid SCHEMBL9626731 | 0.98 | THRA (0.67) | THRATHRBALDH1A1HPGDPTPN11 | |
| Hydrochloric Acid SCHEMBL9626807 | 0.98 | THRA (0.67) | THRATHRBALDH1A1HPGDPTPN11 | |
| SCHEMBL566466 | 0.98 | THRA (0.66) | THRATHRBALDH1A1HPGDPTPN11 | |
| SCHEMBL566426 | 0.95 | THRA (0.62) | THRATHRBALDH1A1HPGDPTPN11 | |
| SCHEMBL177169 | 0.91 | THRA (0.56) | THRATHRBALDH1A1HPGDPTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5328921-A | Antagonist of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1994-07-12 | — | — | US | disclosed |
| US-5208247-A | Antianaphylactic agents or septic shock | AMERICAN CYANAMID COMPANY (US) | 1993-05-04 | — | — | US | disclosed |
| EP-0530444-A1 | Aryl, amide, imide, and carbamate pyridine antagonists of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1993-03-10 | — | — | EP | disclosed |
| US-4994363-A | Silver halide light-sensitive material containing a compound releasing a photographically useful group | FUJI PHOTO FILM CO., LTD. (JP) | 1991-02-19 | — | — | US | disclosed |