SCHEMBL9306436

SCHEMBL9306436

CCCCCCCCCCOc1ccc(C(=O)N(Cc2cccnc2)C(C)=O)cc1C(C)(C)C

nearest known ligand 0.72

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.51
THRB P10828 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9307297 0.89 THRA (0.54) THRATHRB
SCHEMBL9306402 0.83 THRA (0.52) THRATHRB
SCHEMBL9306021 0.83 THRA (0.52) THRATHRB
Iodide SCHEMBL9307942 0.83 THRA (0.50) THRATHRB
SCHEMBL9306261 0.83 MAPT (0.56)
Iodide SCHEMBL9306568 0.81 THRA (0.52) THRATHRB
Iodide SCHEMBL9307336 0.78
Iodide SCHEMBL9307556 0.78
Iodide SCHEMBL9309111 0.78
Iodide SCHEMBL9306384 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5328921-A Antagonist of platelet activating factor AMERICAN CYANAMID COMPANY (US) 1994-07-12 US disclosed
US-5208247-A Antianaphylactic agents or septic shock AMERICAN CYANAMID COMPANY (US) 1993-05-04 US disclosed
EP-0530444-A1 Aryl, amide, imide, and carbamate pyridine antagonists of platelet activating factor AMERICAN CYANAMID COMPANY (US) 1993-03-10 EP disclosed