Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.49 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.49 |
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.46 |
| ▸ | NAAA | Q02083 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | RRM1 | P23921 | 1/20 | 0.45 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.45 |
| ▸ | TLR2 | O60603 | 1/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9306476 | 1.00 | SIRT6 (0.49) | SIRT6SIRT1DPP7FNTAFNTB | |
| SCHEMBL4948525 | 0.98 | SIRT6 (0.51) | SIRT6SIRT1DPP7FNTAFNTB | |
| SCHEMBL4950657 | 0.98 | SIRT6 (0.51) | SIRT6SIRT1DPP7FNTAFNTB | |
| SCHEMBL4949210 | 0.98 | SIRT6 (0.51) | SIRT6SIRT1DPP7FNTAFNTB | |
| SCHEMBL506609 | 0.85 | SIRT6 (0.67) | SIRT6SIRT1DPP7EPHX1NAAA | |
| SCHEMBL9306622 | 0.85 | SIRT6 (0.48) | SIRT6SIRT1DPP7FNTAFNTB | |
| SCHEMBL9306626 | 0.85 | SIRT6 (0.48) | SIRT6SIRT1DPP7FNTAFNTB | |
| SCHEMBL506608 | 0.85 | SIRT6 (0.67) | SIRT6SIRT1DPP7EPHX1NAAA | |
| SCHEMBL25021992 | 0.82 | LPAR3 (0.65) | NAAALPAR3TLR2LPAR1 | |
| SCHEMBL19839845 | 0.82 | SIRT6 (0.63) | SIRT6SIRT1DPP7FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347007-A | Mesylated hydroxymethyl compound treated with alkali metal chloride or quaternary ammonium chloride to form chloromethylamide compound | E. R. SQUIBB & SONS, INC. (US) | 1994-09-13 | — | — | US | disclosed |
| US-5260448-A | Treating a vinyl bromide containing compound with a metal carbonate cyclizing agent | E. R. SQUIBB & SONS, INC. (US) | 1993-11-09 | — | — | US | disclosed |