Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31302506 | 0.68 | PTPN2 (0.43) | GLAHDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL7759218 | 0.68 | HDAC1 (0.64) | GLAHDAC1L3MBTL1GAAMAPK1 | |
| SCHEMBL9684032 | 0.67 | GLA (0.61) | GLAMAPK1KDM4EALDH1A1HPGD | |
| SCHEMBL1697881 | 0.67 | CDC7 (0.47) | GLAHDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL25237575 | 0.66 | MAPT (0.49) | GLAHDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL31207848 | 0.66 | MAPT (0.49) | GLAHDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL31302532 | 0.66 | LMNA (0.51) | GLAHDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL2079547 | 0.65 | GLA (0.58) | GLAL3MBTL1GAAMAPK1TSHR | |
| SCHEMBL16475083 | 0.65 | MAPT (0.48) | HDAC3HDAC4HDAC1HDAC6L3MBTL1 | |
| SCHEMBL13144354 | 0.65 | PTPN2 (0.43) | GLAHDAC3HDAC4HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5360812-A | Fused 1,2,5-oxadiazole-2-oxides and their use | CASSELLA AKTIENGESELLSCHAFT (DE) | 1994-11-01 | — | — | US | disclosed |