Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL9308246 | 0.98 | — | — | |
| Iodide SCHEMBL9305776 | 0.96 | THRA (0.46) | — | |
| Iodide SCHEMBL9306918 | 0.92 | THRA (0.44) | — | |
| Iodide SCHEMBL9307606 | 0.92 | THRA (0.44) | — | |
| Iodide SCHEMBL9306897 | 0.92 | SMPD1 (0.49) | SMPD1 | |
| Iodide SCHEMBL9308198 | 0.92 | THRA (0.47) | — | |
| Iodide SCHEMBL9307354 | 0.92 | THRA (0.47) | — | |
| Iodide SCHEMBL9306917 | 0.90 | — | — | |
| Iodide SCHEMBL9307680 | 0.90 | SMPD1 (0.46) | SMPD1 | |
| Iodide SCHEMBL9565573 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5328921-A | Antagonist of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1994-07-12 | — | — | US | disclosed |