Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.46 |
| ▸ | NMT1 | P30419 | 1/20 | 0.45 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | SENP5 | Q96HI0 | 1/20 | 0.42 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9306602 | 0.91 | NMT1 (0.43) | KDM4ECHRM5CHRM2CHRM3NMT1 | |
| SCHEMBL9024033 | 0.90 | SENP5 (0.48) | NMT1CXCR4ALDH1A1DRD2KMT2A | |
| SCHEMBL9024516 | 0.90 | SENP5 (0.48) | NMT1CXCR4ALDH1A1DRD2KMT2A | |
| Hydrochloric Acid SCHEMBL9305357 | 0.90 | NMT1 (0.43) | KDM4ECHRM5CHRM2CHRM3NMT1 | |
| Hydrochloric Acid SCHEMBL9304756 | 0.89 | SENP5 (0.48) | CHRM5CHRM2CHRM3NMT1CXCR4 | |
| Hydrochloric Acid SCHEMBL9306109 | 0.89 | SENP5 (0.48) | CHRM5CHRM2CHRM3NMT1CXCR4 | |
| Hydrochloric Acid SCHEMBL9306734 | 0.87 | NMT1 (0.43) | KDM4ECHRM5CHRM2CHRM3NMT1 | |
| Hydrochloric Acid SCHEMBL9024501 | 0.83 | CXCR4 (0.51) | KDM4ENMT1CXCR4ALDH1A1DRD2 | |
| Oxalic Acid SCHEMBL9025105 | 0.81 | TAAR1 (0.49) | KDM4ECXCR4ALDH1A1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL9306644 | 0.80 | SENP5 (0.47) | KDM4ECHRM5CHRM2CHRM3NMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5338735-A | For treatment of central nervous system disorders | LILLY INDUSTRIES LIMITED (GB) | 1994-08-16 | — | — | US | disclosed |