SENP5

Sentrin-specific protease 5 · Q96HI0 · SENP5 on Sugi Atlas →

1,921 patent compounds predicted against SENP5, 1,007 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL485276 SCHEMBL485276 0.46 19/20
SCHEMBL4604537 SCHEMBL4604537 0.60 18/20
SCHEMBL485085 SCHEMBL485085 0.58 18/20
SCHEMBL485651 SCHEMBL485651 0.57 18/20
SCHEMBL4632932 SCHEMBL4632932 0.52 18/20
SCHEMBL4604692 SCHEMBL4604692 0.50 18/20
SCHEMBL9219768 SCHEMBL9219768 0.50 18/20
SCHEMBL484955 SCHEMBL484955 0.47 18/20
SCHEMBL485732 SCHEMBL485732 0.46 18/20
SCHEMBL485260 SCHEMBL485260 0.56 17/20
SCHEMBL485298 SCHEMBL485298 0.56 17/20
SCHEMBL9595149 SCHEMBL9595149 0.56 17/20
SCHEMBL9374999 SCHEMBL9374999 0.53 17/20
SCHEMBL9213589 SCHEMBL9213589 0.52 17/20
SCHEMBL4604734 SCHEMBL4604734 0.50 17/20
SCHEMBL485661 SCHEMBL485661 0.47 17/20
SCHEMBL4604976 SCHEMBL4604976 0.63 16/20
Hydrochloric Acid Hydrochloric Acid (SCHEMBL9304232) 0.60 16/20
SCHEMBL485458 SCHEMBL485458 0.59 16/20
SCHEMBL4634951 SCHEMBL4634951 0.58 16/20

Clinical trials — most relevant to SENP5 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
A Prospective, Placebo Controlled, Double-Blind, Cross-over Study on the Effects of a Probiotic Preparation (VSL#3) on Metabolic Profile, Intestinal Permeability, Microbiota, Cytokines and Chemokines Expression and Other Inflammatory Markers in Pediatric Patients With Crohn's Disease PHASE4UNKNOWN
PS-341 and Radiation to Treat Advanced Cancer of the Head and Neck PHASE1COMPLETED
Inhibition of SENP1 for the Suppression of OS Growth and Metastasis nanUNKNOWN
Evaluation of Prognostic Factors: From Breast Cancer to Bone Metastases nanUNKNOWN
Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis nanUNKNOWN
Apoptosis Markers in Aggressive Periodontitis nanCOMPLETED
Autophagy Bladder Cancer nanUNKNOWN
Clinical Manifestations and Biomarkers in Amyotrophic Lateral Sclerosis Type 4 and Other Inherited Neurological Disorders of RNA Processing nanRECRUITING
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Integrated Proteomic HPLC-ESI-MS Analysis of Salivary Peptides of Preterm Newborns: a Pilot Study nanCOMPLETED
Analysis of the Variation in Caspase-8 Availability and Cleavage in Oral Squamous Cell Carcinoma nanUNKNOWN
Circulating Markers That Underlie the Transition From Compensated Hypertrophy to Heart Failure nanRECRUITING
Identification of a New Blood Biomarker for the Diagnosis and Prognosis of Liposarcomas nanRECRUITING
Fatty Acid Binding Proteins and Markers of Cellular Senescence in Cancer Survivors nanNOT_YET_RECRUITING
Next Generation Sequencing in Intrahepatic Cholangiocarcinoma nanUNKNOWN
Biomarkers in Tumor Samples From Younger Patients With Neuroblastoma nanCOMPLETED
Genetic Determinants of Sudden Cardiac Death nanCOMPLETED
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA nanRECRUITING
Patient's Derived Organoids for Drug Screening in Glioblastoma nanNOT_YET_RECRUITING
Circulating Markers for Ischemic Heart Disease nanRECRUITING
Genetic Mechanisms of Chronic Obstructive Pulmonary Disease (COPD) nanCOMPLETED
Characterization of Microbiological and Genetic Features in Prostate Cancer and Their Association with Disease Stage nanENROLLING_BY_INVITATION
Diagnostic Potential of UCHL1 in Acute Decompensated Heart Failure nanCOMPLETED
Long Term Prediction of MASH-related HCC Risk by Proteomics nanNOT_YET_RECRUITING
PCD New Gene Discovery nanCOMPLETED
Gene Mutations and Rescue in Human Congenital Diaphragmatic Hernia nanUNKNOWN
The Surem TRAF3IP2 Level and Atherosclerotic Plaque Development in Human nanUNKNOWN
Identification of New FTLD Genes nanUNKNOWN
Chromosome 5Q Gene Variants and Asthma-Related Traits nanCOMPLETED
Early Diagnosis of Pancreatic Cancer Via Deciphering Multi-modal Immunological Signatures nanNOT_YET_RECRUITING

Related proteins — ESM-2 sequence neighbours (a SENP5 binder may also engage these)

ProteinNameSimilarity
Q8WP32 1.000 Q8WP32 →
Q6NXL6 1.000 Q6NXL6 →
Q3V089 0.994 Q3V089 →
Q86XD8 0.993 Q86XD8 →
A2AKX3 0.993 A2AKX3 →
A1YFX5 0.992 A1YFX5 →
Q28DZ0 0.992 Q28DZ0 →
E1BC15 0.992 E1BC15 →
F1M5M3 0.991 F1M5M3 →
Q8N7Z5 0.991 Q8N7Z5 →
Q8C0P0 0.991 Q8C0P0 →
Q5VWN6 0.991 Q5VWN6 →
A4IGL8 0.991 A4IGL8 →
Q90ZS6 0.991 Q90ZS6 →
Q9D350 0.991 Q9D350 →
Q69554 0.991 Q69554 →
P46200 0.990 P46200 →
P10244 0.990 P10244 →
Q92628 0.990 Q92628 →
Q6AXY9 0.990 Q6AXY9 →
Q7Z333 0.990 Q7Z333 →
Q8BJS8 0.990 Q8BJS8 →
CDCA2 Cell division cycle-associated protein 2 0.990 landscape →
Q6KAQ7 0.990 Q6KAQ7 →
A2T7G6 0.990 A2T7G6 →
Q4V7J0 0.990 Q4V7J0 →
Q5DW34 0.990 Q5DW34 →
Q0VAV2 0.990 Q0VAV2 →
P56716 0.990 P56716 →
Q9D4V4 0.990 Q9D4V4 →