⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL52748 | 0.79 | — | — | |
| SCHEMBL8502472 | 0.58 | — | — | |
| SCHEMBL8630963 | 0.58 | — | — | |
| SCHEMBL18399226 | 0.58 | — | — | |
| SCHEMBL895443 | 0.58 | — | — | |
| SCHEMBL508305 | 0.58 | — | — | |
| SCHEMBL790684 | 0.58 | — | — | |
| SCHEMBL1876585 | 0.58 | — | — | |
| SCHEMBL5675312 | 0.58 | — | — | |
| SCHEMBL8627378 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292737-A | Inhibit protein kinase activity; antiinflammatory/antitumor agents; treatment for cardiovascular disorders | SPHINX PHARMACEUTICALS CORPORATION (US) | 1994-03-08 | — | — | US | claimed |
| US-5292737-A | Inhibit protein kinase activity; antiinflammatory/antitumor agents; treatment for cardiovascular disorders | SPHINX PHARMACEUTICALS CORPORATION (US) | 1994-03-08 | — | — | US | disclosed |