SCHEMBL9307057

SCHEMBL9307057

Cc1cc(N(C)C)ccc1N=Nc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.51
MEN1 O00255 10/20 0.51
KMT2A Q03164 10/20 0.51
ALDH1A1 P00352 6/20 0.51
POLB P06746 4/20 0.51
NPSR1 Q6W5P4 2/20 0.51
LMNA P02545 1/20 0.51
HTT P42858 1/20 0.51
NPC1 O15118 7/20 0.50
RAB9A P51151 7/20 0.50
TDP1 Q9NUW8 7/20 0.50
MAPK1 P28482 5/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
ATM Q13315 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.48
TNNI3 P19429 1/20 0.48
TNNT2 P45379 1/20 0.48
TNNC1 P63316 1/20 0.48
KEAP1 Q14145 1/20 0.48
NFE2L2 Q16236 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9307054 1.00 MAPT (0.51) MAPTMEN1KMT2AALDH1A1POLB
SCHEMBL11508824 0.85 NPC1 (0.62) MAPTMEN1KMT2AALDH1A1POLB
SCHEMBL8611566 0.84 MAPT (0.44) MAPTMEN1KMT2AALDH1A1POLB
SCHEMBL2384567 0.83 MAPT (0.64) MAPTMEN1KMT2AALDH1A1POLB
SCHEMBL7987030 0.83 MAPT (0.64) MAPTMEN1KMT2AALDH1A1POLB
SCHEMBL7987027 0.83 MAPT (0.64) MAPTMEN1KMT2AALDH1A1POLB
SCHEMBL2384564 0.83 MAPT (0.64) MAPTMEN1KMT2AALDH1A1POLB
SCHEMBL8216589 0.83 MAPT (0.49) MAPTMEN1KMT2AALDH1A1POLB
SCHEMBL8216588 0.83 MAPT (0.49) MAPTMEN1KMT2AALDH1A1POLB
SCHEMBL112231 0.82 KMT2A (0.55) MAPTMEN1KMT2AALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5332521-A Ferroelectric liquid crystal composition, liquid crystal optical device produced by using the ferroelectric liquid crystal composition, and method of producing the liquid crystal optical device IDEMITSU KOSAN CO., LTD. (JP) 1994-07-26 US disclosed
EP-0352637-B1 Ferroelectric liquid crystal composition, liquid crystal optical device produced by using the ferroelectric liquid crystal composition, and method of producing the liquid crystal optical device IDEMITSU KOSAN CO (JP) 1994-03-30 EP disclosed
US-5200108-A Flexible substrates supporting layer of liquid crystal material and non-liquid crystalline polymer IDEMITSU KOSAN CO., LTD. (JP) 1993-04-06 US disclosed
EP-0352637-A2 Ferroelectric liquid crystal composition, liquid crystal optical device produced by using the ferroelectric liquid crystal composition, and method of producing the liquid crystal optical device IDEMITSU KOSAN COMPANY LIMITED (JP) 1990-01-31 EP disclosed