Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A1 | Q13285 | 1/20 | 0.61 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.58 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | LTA4H | P09960 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16584080 | 1.00 | NR5A1 (0.61) | NR5A1KEAP1NFE2L2NPC1RAB9A | |
| SCHEMBL15923173 | 1.00 | NR5A1 (0.61) | NR5A1KEAP1NFE2L2NPC1RAB9A | |
| SCHEMBL28006584 | 1.00 | NR5A1 (0.61) | NR5A1KEAP1NFE2L2NPC1RAB9A | |
| SCHEMBL29038706 | 1.00 | NR5A1 (0.61) | NR5A1KEAP1NFE2L2NPC1RAB9A | |
| SCHEMBL5991663 | 1.00 | NR5A1 (0.61) | NR5A1KEAP1NFE2L2NPC1RAB9A | |
| SCHEMBL28651767 | 1.00 | NR5A1 (0.61) | NR5A1KEAP1NFE2L2NPC1RAB9A | |
| SCHEMBL6717278 | 1.00 | NR5A1 (0.61) | NR5A1KEAP1NFE2L2NPC1RAB9A | |
| SCHEMBL15923618 | 1.00 | NR5A1 (0.61) | NR5A1KEAP1NFE2L2NPC1RAB9A | |
| SCHEMBL2401164 | 0.98 | KEAP1 (0.59) | NR5A1KEAP1NFE2L2NPC1RAB9A | |
| SCHEMBL15923077 | 0.96 | NR5A1 (0.58) | NR5A1KEAP1NFE2L2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5328921-A | Antagonist of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1994-07-12 | — | — | US | disclosed |
| US-5208247-A | Antianaphylactic agents or septic shock | AMERICAN CYANAMID COMPANY (US) | 1993-05-04 | — | — | US | disclosed |
| EP-0530444-A1 | Aryl, amide, imide, and carbamate pyridine antagonists of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1993-03-10 | — | — | EP | disclosed |