Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.37 |
| ▸ | CPA1 | P15085 | 2/20 | 0.36 |
| ▸ | CPB1 | P15086 | 1/20 | 0.36 |
| ▸ | CPA3 | P15088 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10893575 | 0.82 | ELANE (0.40) | ELANEKMT2AMEN1POLBNPSR1 | |
| SCHEMBL9307170 | 0.81 | ELANE (0.39) | ELANEKMT2AMEN1POLBNPSR1 | |
| SCHEMBL10891085 | 0.79 | ALDH1A1 (0.40) | ELANEKMT2AMEN1NPC1RAB9A | |
| SCHEMBL10892684 | 0.78 | ELANE (0.40) | ELANEKMT2AMEN1POLBNPSR1 | |
| SCHEMBL8972330 | 0.78 | KMT2A (0.52) | KMT2AMEN1POLBNPC1RAB9A | |
| Ammonia Solution, Strong SCHEMBL10889818 | 0.77 | KMT2A (0.51) | KMT2AMEN1POLBNPC1RAB9A | |
| SCHEMBL10895295 | 0.77 | KMT2A (0.51) | KMT2AMEN1POLBNPC1RAB9A | |
| SCHEMBL10890468 | 0.76 | POLB (0.40) | ELANEKMT2AMEN1POLBNPC1 | |
| Dimethylamine SCHEMBL10893052 | 0.76 | ALDH1A1 (0.50) | KMT2AMEN1POLBNPC1RAB9A | |
| SCHEMBL9305254 | 0.75 | POLB (0.41) | KMT2AMEN1POLBCPA1CPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| US-4612049-A | BENZOTHI ZOLYL THIO-, BENZIMIDAZOLYLTHIO- OR BENZOXAZOLYLTHIO-SUBSTITUTED CARBOXY ACID | CIBA-GEIGY CORPORATION (US) | 1986-09-16 | — | — | US | disclosed |